Metrolab Blog

THERMO MAbPac™ RP LC Columns

Use the new Thermo Scientific™ MAbPac™ RP columns for high-performance reversed-phase (RP) HPLC and LC/MS characterization of monoclonal antibodies (mAbs), fragments, variants, antibody drug conjugates (ADCs), PEGylated proteins, and bispecific proteins. These columns have excellent resolution, long column lifetime, and low carry-over. The surface chemistry, particle size, and pore size, have been optimized for high resolution separations.

Compatible with organic solvent used in HPLC and MS under RP conditions
Resin is based on a hydrophobic supermacroporous 4µm polymer particles
Stable at extreme pH (0 to 14) and high temperature (up to 110 °C)

Efficient with low carry over
1,500Å large pore size polymeric resin
Efficient separation of protein molecules with very low carry over

Designed for reversed-phase biomolecule LC and LC/MS separations
Superior resolution power for monoclonal antibodies and related substances
High efficiency with low carry-over
Excellent MS compatibility
Wide operating pH range: 0 to 14
High temperature stability: up to 110°C
High throughput

For more information about the available BioLC columns from THERMO, download NOW the «Innovative solutions for mAb analysis and characterization» brochure