Characterizing Therapeutic Monoclonal Antibodies

Numerous techniques and supporting regulatory frameworks have been developed to promote consistency throughout mAb development and production. Each of the chromatographic techniques described in this application note for the analysis and characterization of mAbs is associated with various advantages and limitations, meaning researchers need to be aware of changing trends and developments within the field to ensure that the selected method best suits their immediate and long-term goals. LC remains one of the most powerful and versatile techniques available for the characterization of mAbs and other molecules.
With therapeutic mAbs looking set to continue their success in clinical settings, remaining on top of the latest chromatography developments is paramount for any researcher.