Worldwide, researchers are searching for ways to boost the immune system’s ability to fight cancer; one such way is by developing novel therapeutics within the pharmaceutical/ biopharmaceutical industry.
Technologies such as liquid chromatography and mass spectrometry (LC-MS) can provide insights into drug structure and activity at the cellular level, providing greater confidence in drug discovery, quality, and purity.
Recent developments in LC-MS hardware, software, columns, and sample prep offer a new paradigm in drug discovery—and LC-MS techniques are being applied to unravel complex cascades of protein interactions that underlie disease states.
Peptide mapping is one way to measure critical quality attributes (CQA) required for the characterization of biotherapeutic proteins.
SMART SAMPLE PREPARATION
Characterize and quantitate proteins more quickly, easily, and reproducibly than ever before with simple sample preparation kits. Offering a significant improvement over insolution protein digestion, Thermo Scientific™ SMART™ Digest Kits can typically digest monoclonal antibodies in less than an hour and are compatible with automation.