Metrolab Blog

SOLA SPE Products – Increase your MS sensitivity

Thermo Scientific SOLA products are designed for bioanalytical and clinical research analysts who are tasked with providing high quality analytical results from complex biological samples in a high throughput environment, while complying with strict legislation. These demands are compounded by the continued push to higher efficacy drugs and long acting formulations which continue to drive sensitivity requirements to lower levels to enable accurate quantification.

Increase your MS sensitivity
Up to 20 times increase in sensitivity can be achieved by loading a large volume of sample and eluting in a low volume.
In the following example 500μL of human plasma was loaded onto the SOLAμ plate for the analysis of niflumic acid. The compound was eluted in 25μL, providing a 20 times increase in concentration whilst maintaining excellent precision.

THERMO_SOLA_MS sensitivity_01

THERMO_SOLA_MS sensitivity_02

For more information about SOLA SPE Products watch the video below: