Metrolab Blog

SOLA SPE Products – Directly scale down the volumes used in analytical methods

Thermo Scientific SOLA products are designed for bioanalytical and clinical research analysts who are tasked with providing high quality analytical results from complex biological samples in a high throughput environment, while complying with strict legislation. These demands are compounded by the continued push to higher efficacy drugs and long acting formulations which continue to drive sensitivity requirements to lower levels to enable accurate quantification.

Sample limited assays
SOLAμ allows you to directly scale down the volumes used in analytical methods, allowing for a reduction in sample usage and eliminating issues caused by evaporation, without compromising the sensitivity of your assay. This is also an important consideration when sample volumes are limited. The following example shows that by loading 25μL of niflumic acid sample onto the SOLAμ plate and eluting in a total volume of 25μL, a ten-fold decrease in sample volume was achieved when compared to a traditional scale higher bed weight product. Equivalent method performance and high levels of reproducibility provided by SOLA technology were still maintained.

THERMO_SOLA_Limited sample_01

THERMO_SOLA_Limited sample_02

For more information about SOLA SPE Products watch the video below: