Performance evaluation of MAbPac RP columns for monoclonal antibody IdeS subunit analysis

This application note describes the applicability of middle-up techniques for biotherapeutics characterization. Shows fast, efficient separation using reversed-phase chromatography with Thermo Scientific™ MAbPac™ RP columns for the characterization of mAb variants. Demonstrates the effect of column i.d. on the resolution, loading capacity, mobile phase composition, and ease of use.