Metrolab Blog

O-glycan profiling using HPAE-PAD hyphenated with HRAM-MS

Authors : Manali Aggrawal, Sachin Patil, and Jeffrey Rohrer
Thermo Fisher Scientific, Sunnyvale, CA, United States

High-performance anion-exchange coupled with pulsed amperometric detection (HPAE-PAD) is a commonly used method for glycan analysis. Learn how hyphenating HPAE-PAD with a high-resolution accurate mass (HRAM) mass spectrometer allows for the analysis of O-glycan structures released from four different glycoproteins .

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