Metrolab Blog

New Software Solutions Unlock Deep Analytical Insights (Proteomics)

ASMS – Day 4 – New Software Solutions Unlock Deep Analytical Insights

Here are the newest features:

The new cloud-based Thermo Scientific™ Ardia™ platform integrates data across multiple chromatography and mass spectrometry instruments, letting biopharmaceutical and proteomics scientists share previously siloed data, simplifying analyses and unlocking deeper insights into new diagnostics and therapies that could reach the point of care sooner.

A complete solution for biotherapeutic characterization

The newest Thermo Scientific™ BioPharma Finder™ 5.1 software offers a complete solution for oligonucleotide analysis and biotherapeutic characterization workflows, providing increased confidence in results by comprehensively characterizing mass spectrometry data using advanced algorithms. Oligonucleotide-based biotherapeutics present unique challenges for characterization due to their complexity. The new software provides an enhanced suite of built-for-purpose tools to overcome these challenges and meet the needs of this rapidly growing field, quickly and confidently turning complex data into meaningful results. Improvements to the kinetic prediction model for oligonucleotides enable more confident prediction and matching. Improved data review tools and tables offer streamlined review and results reporting of complex oligonucleotide data sets.

Leveraging AI to redefine proteomics research capabilities

Proteomics scientists can now benefit from the newest Thermo Scientific™ Proteome Discoverer™ 3.0 software in combination with the CHIMERYS intelligent search algorithm by MSAID, leveraging artificial intelligence to more fully interpret data generated by Thermo Scientific™ Orbitrap™ mass spectrometers. This innovative approach substantially increases the number of unique peptide identifications, improves protein coverage and quantitation capabilities, and enables scientists to discover more in their data. The new intelligent search algorithm also facilitates higher throughput analysis and wide-isolation window data-dependent acquisition for synergistic performance enhancements. This deeper mining of data expands the ways in which proteomics scientists can acquire and apply their data.

Improve untargeted small molecule workflows with new peak detection and quality algorithms

Small molecule researchers can now leverage a faster and more sensitive peak detection algorithm with the newest Thermo Scientific™ Compound Discoverer™ 3.3 software to detect more compounds in less time. Filtering large data sets down to relevant compounds is now easier than ever by using the new peak quality functionality to streamline data processing and review. Improve confidence in compound annotations through MSn spectral tree search capabilities in tandem with the Thermo Scientific™ mzCloud spectral library to address the most challenging unknown compounds. Compound Discoverer 3.3 software, which has been optimized for processing large datasets and detecting low-abundance compounds, will support scientists in metabolomics, pharmaceutical, environmental, food safety, clinical, and forensics applications to acquire the results they need to drive science forward.

And that’s a wrap on the 70th American Society for Mass Spectrometry (ASMS) Conference in Minneapolis!