Metrolab Blog

Leveraging complementary selectivity to solve challenging analytical problems

In this application we demonstrate the value of a biphenyl chemistry for the analysis of mycotoxins. Commonly, mycotoxin applications are developed around a C18 separation column. This column uses the hydrophobic properties of the target mycotoxins as the basis of separation from the matrix background. An alternate chemistry, such as the Thermo Scientific™ Accucore™ Biphenyl column will provide a different selectivity to the mycotoxins. This is because the predominant forces governing the separation in a biphenyl column are the pi-pi interactions of the electron rich stationary phase and the pi bonds of the mycotoxins.

Download the full application note here.