Metrolab Blog

Expanding the Boundaries of Light Scattering for Macromolecules

In the past four decades, light scattering detection (LS) has become a widely used technique to obtain the supposed “absolute” or true molecular weight of macromolecules such as synthetic polymers, biopolymers, proteins, and antibodies. When coupled with size exclusion chromatography (SEC), molecular weight and size, as well as aggregation or branching can be investigated to provide analytical scientists with a powerful characterisation tool for these large molecules.

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