Metrolab Blog

Cost-efficient Purification of Antibodies

How to obtain an efficient and reliable purification of antibodies?
The commercial success of antibody pharmaceuticals, depends on a careful consideration of the production costs. Process efficiency is strongly influenced by the binding capacity of the used resin, as this determines the amount of product that can be purified per chromatographic cycle.

YMC_Purification of Antibodies_small
A comparison study was conducted and BioPro IEX S30 was tested alongside competitive resins for the purification of a monoclonal, pharmaceutical antibody under various method conditions. This study is available for download here and confirms a significant gain in dynamic binding capacity due to the use of the YMC IEX resin.