Allowed changes of your European Pharmacopoeia HPLC methods

Are you responsible for implementing monographs from the European Pharmacopoeia (Ph. Eur.) into your routine analysis?

Are you not quite sure which optimizations you are allowed to take to ensure the reproducibility of your results?

Because most pharmacopoeia methods are developed on older chromatographic material it is worthwhile to already switch in implementation to a more innovative column material for which not only support of the manufacturer is guaranteed, but also a consistent manufacturing process. For this, usually small changes in method parameters are necessary and your gain will be reproducible and robust results. Day by day, year by year, column by column.

Download our helpful overview of allowed changes to methods in the European Pharmacopoeia and we’re happy to provide you with a personal consultation.